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Denosyl (Adenosylmethionine)

DENOSYL is a nutritional supplement intended for dogs and cats with liver diseases.
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Cats & Dogs 0-12 lbs (90 mg)
Dogs 13-34 lbs (225 mg)
Dogs 35+ lbs (425mg)
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  • Generic Name:
  • Adenosylmethionine
  • Brand Name:
  • Denosyl by Nutramax Labs
Denosyl Ingredients

  • 90 mg
  • S-Adenosylmethionine (Small dogs & cats))
  • 225 mg
  • S-Adenosylmethionine (Medium dogs & Large cats)
  • 425 mg
  • S-Adenosylmethionine (Large dogs)


DENOSYL is a nutritional supplement that provides an effective therapeutic agent for liver support in dogs and cats. The ingredient, S-Adenosylmethionine (SAMe), is a naturally occurring compound that is found in almost every tissue and fluid in the body. DENOSYL can be used in all cases where the liver requires some support such as...
  • - acute or chronic liver damage
  • - mild liver disease
  • - regular treatment of liver damaging drugs (Phenobarbital, NSAIDs, etc.)

SAMe is used by the liver in many biochemical pathways. It has been shown to strengthen the cell membranes; thus, improving liver cell function and providing the building blocks for antioxidants used by the liver.


  • - Non-prescription (OTC) nutritional supplement
  • - Natural chemical produced from the amino acid called methionine
  • - Protects and supports healthy liver function
  • - Improves antioxidant levels that protect cells from toxins
  • - Protects and repairs liver cells
  • - Easy-to-administer, palatable tablets that can be split easily
  • - Available in different sized tablets...
        • 90 mg (Cats & small dogs up to 12 lbs)
        • 225 mg (Large cats and medium sized dogs 13 to 34 lbs)
        • 425 mg (Large dogs over 35 lbs)
        • 225 mg Chews (Dogs of all sizes)

DENOSYL Warnings

  • - Do not give DENOSYL to any animal that has had an allergic reaction to SAMe
  • - Blood tests are necessary to monitor liver values

Details About Denosyl
"DENOSYL is a nutritional supplement intended for dogs and cats with liver diseases."
Denosyl Is Used To Treat These Symptoms

  • Liver Disease

Possible Side Effects When Using Denosyl

  • No Reported Side Effects

Although side effects while taking DENOSYL are rare, contact your veterinarian if you notice any behavioral or physiological changes in your pet.
Our Information Is Not Intended To Replace The Advice Of Your Veterinarian
"Do not use our product information for diagnostic purposes. Always take your pet to your veterinarian to obtain a diagnosis and course of treatment. Only your veterinarian is qualified to assess all possible side effects, interactions, precautions, warnings and possible allergic reactions relating to the use of this product or drug with your pet."

DENOSYL Directions

  • - Use as directed by your veterinarian
  • - Store DENOSYL at room temperature and away from light and moisture
  • - Duration of administration depends on the condition being treated, response to the medication and
    • development of any adverse effects
  • - Allow your pet access to plenty of water
  • - DENOSYL should be administered on an empty stomach
  • - 1 hour before or 2 hours after a meal
  • - If giving more than one tablet, it is recommended that you administer tablets in two separate doses


Dosage for DOGS and CATS Body Weight (lbs)

Dogs and Cats up to 12lbs
  • - Denosyl 90mg
        • 1 tablet daily

Dogs 13 to 34lbs
  • - Denosyl 225mg
        • 1 tablet daily

Dogs 35 to 65lbs
  • - Denosyl 425mg
        • 1 tablet daily

Dogs 66 to 120lbs
  • - Denosyl 425mg
        • 2 tablets daily

Dogs 121 lbs and over
  • - Denosyl 425mg
        • 3 tablets daily

Dosage FAQs

  • - In the case of a missed dose of DENOSYL, give it as soon as you remember or just wait until it is
    • time to give the next dose. DO NOT GIVE A DOUBLE DOSE OF DENOSYL.
  • - In the case of an overdose of DENOSYL, seek attention from your veterinarian immediately.

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Tablets Cats & Dogs 0-12 lbs (90 mg)
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Tablets Dogs 13-34 lbs (225 mg)
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Tablets Dogs 35+ lbs (425mg)
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Chewables Dogs of All Sizes (225mg)