Cisapride Compound

• Cisapride is available by prescription only.

• Cisapride belongs to the benzamide class of drugs.

• Benzamide drugs are used as a motility enhancement drug in dogs and cats.

• Motility disorders of the gastrointestinal (GI) tract are a common clinical problem in companion animals.

• Cisapride is used to treat...

• chronic constipation

• megacolon

• megaesophagus

• acid reflux disease

• The muscles in the stomach contract to pass food at a certain pace known as motility.

• Motility can be inconsistent or abnormal due to a number of disorders.

• Reduced motility leads to a build-up of food in the stomach which causes bloating and nausea.

• Cisapride increases the release of acetylcholine, which in turn stimulates the smooth muscle in the digestive tract to contract more frequently.

• Cisapride compound can only be dispensed in 180 day increments.

• Cisapride compound is available in...

• A capsule

• An oral suspension

• A transdermal cream

• Keep out of the reach of children and pets.

• Do not use in pets with known allergies to cisapride.

• Do not be use in animals that are pregnant or lactating.

• Notify your veterinarian if your pet has bloody stool or vomit while taking cisapride.

• Do not give Cisapride to pets with an obstruction or perforation in their digestive tract.

• Consult your veterinarian if your pet is also taking...

• vitamins

• supplements

• cimetidine

• itraconazole

• ketoconazole

• ranitidine

• anticholinergic agents

• anticoagulants

• diazepam

• Shake oral suspensions well before use.

• Store at room temperature.

• Use as directed by your veterinarian.

• Follow the instructions printed on the prescription label.

• Be sure to complete the prescription to ensure a full recovery, even if your pet seems to be improving, unless instructed otherwise by your veterinarian.

• Duration of administration depends on the condition being treated, response to the medication, and development of any adverse effects.

• Allow your pet access to plenty of water.

• Give cisapride at least 30 minutes before feeding.

• Store at room temperature.

• Shake suspensions well before use.

• In the case of a missed dose of cisapride, give it as soon as you remember, or wait until it is time to give the next dose. DO NOT GIVE A DOUBLE DOSE OF CISAPRIDE.

• In the case of an overdose of cisapride, seek attention from your veterinarian.

• The following symptoms could be signs of an overdose...

• severe diarrhea

• abdominal cramps

• seizures

• Allergic reactions and serious side effects are rare, but in the case of an allergic reaction or a serious side effect you should seek immediate veterinary attention.

• Some common signs of an allergic reaction or serious side effect are...

• facial swelling

• breathing difficulties

• hives

• shock

• seizures

• pale gums

• cold limbs

• coma