Proin Extended-Release (Cannot ship to AR, IA, LA, OR, and WV)

• Proin ER is available by prescription only.

• Proin ER works as an adrenergic agent to treat urinary incontinence in dogs.

• Proin ER uses patented extended-release technology to administer the effective concentration of medication throughout the day in a once daily dose.

• Proin ER contains the ingredient phenylpropanolamine, which works to tighten the sphincter muscle in the bladder to help control urine leakage.

• Due to its classification in some states as a controlled substance, Proin ER cannot be shipped to the following states:

• Arkansas

• Iowa

• Louisiana

• Oregon

• West Virginia

• Proin ER is available in different size chewable tablets...

• 18 mg

• 38 mg

• 74 mg

• 145 mg

• Keep out of the reach of children and pets.

• Proin ER is not intended for human use.

• Proin ER should not be used in animals with known allergies to this drug.

• Proin ER may interact with some other medications. Inform your veterinarian of any and all medications your pet may be taking, especially...

• ephedrine

• epinephrine

• any non-steroidal anti-inflammatory drugs (such as aspirin or Rimadyl)

• digoxin

• tricyclic antidepressants (clomipramine)

• beta blockers (atenolol)

• Do not give within two weeks of using any MAOi (such as Preventic Collars, Anipryl, or Selegiline).

• Proin ER should not be used in pregnant or lactating animals.

• Do not use in animals suffering from...

• glaucoma

• enlarged prostate

• hyperthyroidism

• diabetes mellitus

• heart problems

• high blood pressure

• Store at room temperature.

• Use as directed by your veterinarian.

• Follow the instructions on the prescription label.

• Store at room temperature, protected from light and moisture.

• Proin ER should be given with food.

• Monitor your pet after administering Proin to insure that all medication was consumed.

• It may take several days of treatment before urinary incontinence improves.

• It is important not to miss any doses of Proin, as stopping treatment will cause recurrence of symptoms.

• Adverse reactions and serious side effects are rare, but in the case of a more serious side effect, seek veterinary attention immediately.

• Common allergic reactions and serious side effects are...

• facial swelling

• hives

• scratching

• sudden onset of diarrhea

• vomiting

• seizures

• pale gums

• coma