- congestive heart failure
- edema
- high blood pressure (hypertension)
- potassium deficiency
- hyperaldosteronism
- are pregnant or lactating
- have high potassium levels in the blood
- suffer from hypoadrenocorticism
- suffer from Cushing's disease and are taking the medication mitotane
- facial swelling
- hives
- sudden onset of diarrhea
- seizures
- coma
- pale gums