Doxepin

• Doxepin is available by prescription only.

• Doxepin is an extra-label antidepressant with some antihistamine effects.

• Doxepin works by blocking histamine effects, thus reducing itchiness from allergies.

• Doxepin can also be used to treat skin conditions associated with anxiety in dogs.

• Doxepin is available in...

• a capsule

• Keep out of the reach of children and pets.

• Do not use in pets with known allergies to doxepin or any other similar medications (tricyclic antidepressants), like amitriptyline.

• Use with caution in pets that...

• have glaucoma or dry eye syndrome

• are very young or older

• are working dogs

• are nursing

• have a history of seizures

• have problems with urination

• have prostate enlargement

• have thyroid problems

• have heart disease

• have adrenal tumors

• have gastrointestinal tract obstructions

• Do NOT use in pets that have...

• recently used flea and tick collars (within 2 weeks)

• recently taken drugs that are monoamine oxidase inhibitors, like selegiline and amitraz

• an appointment for allergy medication, as this drug can interfere with results of testing.

• Store at room temperature.

• Store protected from light and moisture.

• Give as directed by your veterinarian.

• Follow the instructions printed on the prescription label.

• Store at room temperature, protected from light and moisture.

• Complete the prescription to ensure a full recovery, even if your pet seems to be improving, unless instructed otherwise by your veterinarian.

• Give with or without food.

• Make sure that your pet has access to plenty of water while taking this medication.

• It may take several weeks before doxepin is effective.

• In the case of a missed dose of Doxepin, give it as soon as you remember or wait until it is time to give the next dose. DO NOT GIVE A DOUBLE DOSE OF DOXEPIN.

• In the case of an overdose of Doxepin, seek attention from your veterinarian.

• Common but not serious side effects include...

• sleepiness

• blue-green urine

• excitability 

• dry mouth

• trouble urinating

• vomiting

• decreased appetite

• constipation or diarrhea

• Adverse reactions and serious side effects are rare, but in the case of an adverse reaction or a serious side effect, you should stop Doxepin treatment and seek veterinary attention.

• Some common signs of allergic reactions and serious side effects are...

• seizures

• hyperexcitability 

• coma

• racing heartbeat

• abnormal bleeding

• fever

• low energy