Vetmedin (Pimobendan)

---

Vetmedin Basics

• Vetmedin is available by prescription only.

• Vetmedin, or pimobendan, is a phosphodiesterase III inhibitor with calcium sensitizing properties.

• Vetmedin acts as a vasodilator and a cardiac muscle stimulator.

• Phosphodiesterase inhibitors cause the blood vessels to relax and force the heart to beat more efficiently.

• Vetmedin improves the quality of life in dogs suffering from...

• congestive heart failure (CHF)

• dilated cardiomyopathy, or an enlarged, weakened heart

• Vetmedin comes in four different strengths of beef-flavored chewable tablets:

• 1.25 mg

• 2.5 mg

• 5 mg

• 10 mg

---

Vetmedin Warnings

• Keep out of the reach of children and pets.

• Vetmedin should not be used in dogs with known hypersensitivity or allergy to pimobendan.

• Do not use in dogs with...

• hypertrophic cardiomyopathy, or a thickened heart

• aortic stenosis, or narrowing of the aortic valve

• any other heart condition causing an increase in cardiac output

• Vetmedin should not be given to any dog less than 6 months of age.

• Do not use Vetmedin if your pet is pregnant or lactating.

• Vetmedin can interact with some other medications. Inform your veterinarian of any and all medications your pet may be taking, especially...

• verapamil

• theophylline

• pentoxiphylline

• propranolol

• Vetmedin is not for use in cats.

• Store at room temperature.

---

---

Vetmedin Directions

• Use as directed by your veterinarian.

• Follow the instructions printed on the prescription label.

• Store Vetmedin at room temperature.

• Be sure to complete the prescription to ensure a full recovery, even if your pet seems to be improving, unless instructed otherwise by your veterinarian.

• Duration of administration depends on the condition being treated, the response to the medication, and the development of any adverse effects.

• For best results, give Vetmedin 1 hour before food. This information is taken from Plumb's Veterinary Drug Handbook (5th Edition.)

• Do not give Vetmedin to any dogs less than 6 months of age.

---

Dosage FAQs

• In the case of a missed dose of Vetmedin, give it as soon as you remember or wait until it is time to give the next dose. DO NOT GIVE A DOUBLE DOSE OF VETMEDIN.

• In the case of an overdose of Vetmedin, seek attention from your veterinarian.

• Signs of an overdose include...

• loss of appetite

• weakness

• drowsiness

• diarrhea

• breathing difficulties

• weakness

• fainting

• coughing

• fluid in the lungs or abdomen

---

One of the greatest drugs introduced to veterinary medicine is Vetmedin (pimobendan). Congestive heart failure is a frequently encountered disease in our veterinary patients, and this drug has proven to be the most effective product at our disposal in decades. The beauty of Vetmedin is that it is not only a vasodilator (to decrease the workload on the heart), but it also slows the heart rate and improves contractility. For advanced congestive heart failure, it has been extremely effective. I have personally seen dogs on other vasodilators, dogs that have totally decompensated, normalize just hours after Vetmedin therapy is instituted. Your veterinarian will gladly discuss this product with you if you have a dog in congestive heart failure. It really works well.

---

If you notice any behavioral or physiological changes in your pet while giving Vetmedin, contact your veterinarian immediately.

---

Allergic Reactions and Serious Side Effects

• Allergic reactions and serious side effects are rare, but in the case of an allergic reaction or a serious side effect, seek veterinary attention immediately.

• Some common signs of an allergic reaction or more serious side effect are...

• facial swelling

• breathing difficulties

• fainting

• scratching

• fever

• coma

• shock

• fluid in the lungs or abdomen

• coughing

---