Marquis

• Marquis is available by prescription only.

• Marquis contains the active ingredient ponazuril.

• Marquis is used to treat equine protozoal myeloencephalitis (EPM).

• EPM is caused by Sarcocystis neurona, a parasite.

• Marquis kills Sarcocystis neurona.

• Marquis is an antiprotozoal oral paste for horses.

• The paste is supplied in ready-to-use syringes.

• Each syringe contains 127 grams of paste.

• Each gram of paste contains 150 mg of ponazuril.

• Marquis comes with a dosage ring to help set the appropriate dose.

• Keep out of the reach of children and pets.

• Marquis is for use in horses only.

• Marquis is not intended for human use.

• Use with caution in pregnant or nursing horses.

• Symptoms may worsen when treatment begins.

• Store at room temperature.

• Dispose of partially used syringes after treatment.

• Use as directed by your veterinarian.

• Follow the instructions printed on the prescription label.

• To use Marquis, remove the cap and apply pressure to the plunger until paste is seen at the tip of the syringe barrel.

• Return the cap to tip of paste syringe.

• Determine the weight of your horse.

• Be sure that your horse’s mouth contains no feed before using Marquis.

• To ensure the proper dose, the dosage ring collar and barrel collar should be flush.

• Hold the plunger and rotate the dosage ring with the other hand to match the weight of the horse.

• Remove the cap from the tip of the syringe.

• Deposit the dose onto the back and top of the horse’s tongue.

• Start administering Marquis by putting the syringe tip into the side of your horse’s mouth at the space between the front and back teeth.

• Deposit the paste onto the horse’s tongue by pressing the plunger of the syringe as far as the dosage ring permits.

• Remove the tip of the syringe from the horse’s mouth.

• To help your horse swallow the paste, immediately raise your horse’s head for a few seconds after dosing.

• Clean the tip of the syringe with a clean disposable towel and return the end cap to the tip of the syringe barrel.

• If you believe your horse is experiencing an allergic reaction to Marquis, contact your veterinarian immediately. Signs of an allergic reaction may include...

• facial swelling

• hives

• scratching

• sudden onset of diarrhea

• shock

• seizures

• pale gums

• cold limbs

• coma

• After beginning Marquis, symptoms may worsen. This could include a worsening of the loss of control of body movement. Contact your veterinarian if you notice a loss of control of body movement in your horse, as this could be permanent.